Real-World Evidence

Unlock the potential of Nordic Real-World Data

The Nordic countries, and Denmark in particular, offer unique opportunities for generating real-world evidence (RWE) through high-quality nationwide health registries and the ability to link data across multiple sources.

NIHE helps clients access and use Danish real-world data to generate evidence on:

Disease burden & unmet needs

Patient pathways & treatment patterns

Healthcare resource use & costs

Our real-world evidence process

We support the full RWE process – from study design to publication.

Research question and study design

Protocol development

Data application and access

Statistical analysis

Interpretation

Scientific publication and dissemination

Authorized and Nordic expertise

NIHE is authorized to conduct register-based research through the Danish Health Data Authority and Statistics Denmark. Through our research partners we coordinate RWE projects using data from Denmark, Sweden, Norway and Finland. Our team combines experienced epidemiologists and health economists with medical and scientific writing expertise, enabling us to support the full RWE process.

Clients

NIHE has conducted RWE projects for pharmaceutical and medtech companies, universities, hospitals, and patient organisations. Clients and collaborators include AbbVie, Contura, Hepatology and Gastroenterology, Aarhus University Hospital, Mental Health Services, The Central Region of Denmark, Novartis, Novo Nordisk, Sobi, and The Danish Rheumatism Association.

Case examples

Explore selected examples of NIHE’s real-world evidence studies and peer-reviewed publications:

Burden of disease

In collaboration with The Danish Rheumatism Association, NIHE has estimated prevalence and incidence of inflammatory arthritis in Denmark.

Expected date of publication January 15, 2027

Broader societal impacts of diseases and treatments

NIHE has estimated productivity loss labor market effects in patients with migraines using real-world evidence.

READ THE REPORT →

Real-world based economic evaluation

NIHE has worked with Aarhus University Hospital to document real-world value of faecal microbiota transplantation in patients with Clostridioides difficile.

READ THE ARTICLE →